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Member Research & Reports

Member Research & Reports

AUB Leads a New Study on Multiple Sclerosis and the Glympatic System

Gadolinium-enhanced MR imaging is currently the reference standard to detect active inflammatory lesions in Multiple Sclerosis MS. Knowledge of the patterns and mechanisms of contrast enhancement is vital to limit the radiologic differential diagnosis in the staging and evaluation of MS lesion activity. This paper from the American University of Beirut – Faculty of Health Sciences, describes 1) the pathophysiology of the effect of lymphocyte-driven inflammation in MS, 2) effects of gadolinium on the BBB and glymphatic system, and 3) gadolinium enhancement patterns and artifacts that can mimic lesions in MS.  This paper explores the complexities of Imaging patterns and diagnosis of Multiple Sclerosis and the effect of gadolinium enhancement and gadolinium retention due to the various blood-brain barriers.

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