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Member Research and Reports

Member Research and Reports

BU Study Evaluates Antihistamine Use in Pregnancy

A team led by Boston University School of Public Health researchers has found no “meaningful support” for previous suggestions that antihistamines taken during pregnancy might be linked to increased risks of birth defects. In a study published in the Journal of Allergy and Clinical Immunology: In Practice, researchers with the Boston University School of Public Health Slone Epidemiology Center tested 16 previously hypothesized associations between specific antihistamines and specific birth defects. The team used 1998-2010 data from the Slone Epidemiology Center Birth Defects Study, a multi-center case-control surveillance program of birth defects in North America. The new study was based on interviews with more than 20,000 new mothers. The researchers considered antihistamines that had been suggested in earlier studies to increase risks of certain defects, while also considering other possible risks that might not have been identified in the past.