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DHHS Funding Opportunities

FUNDING OPPORTUNITIES from the Department of Health and Human Services (DHHS)

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Department of Health and Human Services – Centers for Disease Control – Enhancing Global Health Security: Strengthening Public Health Surveillance Systems and Preparedness Globally

Proposal Due Date:                                                           August 9, 2021

Expected Number of Awards:                                        5

Estimated Total Program Funding:                              $300,000

Award Ceiling:                                                                    $0

Award Floor:                                                                       $0

Funding Opportunity Number:                                      CDC-RFA-GH21-2174

Purpose:  Activities under this Notice of Funding Opportunity (NOFO) should focus on protecting and improving public health globally by:  strengthening public health surveillance systems; improving the public health surveillance workforce; improving the interface between public health disease surveillance and laboratory systems; reinforcing emergency surveillance preparedness; enhancing electronic disease surveillance platforms and systems; and enhancing the use of surveillance data for public health action. This NOFO is intended to support global health security partners to develop or continue the implementation of surveillance activities that focus on protecting and improving public health globally through strategic planning, policy, strengthening surveillance capacities and systems through partnerships. These should build and improve regional and country capacities to prevent, detect, respond and control infectious disease outbreaks, strengthen border health security and mitigate public health events of international concern (PHEICs) or other global health threats.

https://www.grants.gov/web/grants/view-opportunity.html?oppId=329410

Department of Health and Human Services – Health Resources and Services Administration – Service Area Competition

Proposal Due Date:                                                           August 13, 2021

Expected Number of Awards:                                        40

Estimated Total Program Funding:                              $99,466,000

Award Ceiling:

Award Floor:

Funding Opportunity Number:                                      HRSA-22-004

Purpose: This notice announces the opportunity to apply for funding under the Health Center Program’s Service Area Competition (SAC). The Health Center Program supports domestic public or private, nonprofit community-based and patient-directed organizations that provide primary health care services to the Nation’s medically underserved populations. The purpose of the SAC notice of funding opportunity (NOFO) is to ensure continued access to comprehensive, culturally competent, high-quality primary health care services for communities and populations currently served by the Health Center Program.

https://www.grants.gov/web/grants/view-opportunity.html?oppId=334144

Department of Health and Human Services – National Institutes of Health – HEAL Initiative: Planning Studies for Initial Analgesic Development [Small Molecules and Biologics] (R61 Clinical Trial Not Allowed)

Letter of Intent Due Date:                                              30 days prior to application due date

Proposal Due Date:                                                           July 19, 2021

Expected Number of Awards:

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Funding Opportunity Number:                                      RFA-NS-21-029

Purpose: Reissue of RFA-NS-21-016: The goal of this funding opportunity announcement (FOA) is to solicit Initial Analgesic Development R61 applications that propose 2-year exploratory/planning awards that are expected to enable a future application for RFA-NS-21-015 HEAL Initiative: Team Research – for Initial Translational Efforts in Non-addictive Analgesic Development [Small Molecules and Biologics] (U19 Clinical Trial Not Allowed). Thus, the limited scope of aims and approach of these applications are expected to establish a strong research team, feasibility, validity, or other technically qualifying results that support, enable, and/or lay the groundwork for a subsequent Team Research U19 application. These R61 awards will support the building of a research team to collect initial data and recruit additional collaborators. The proposal must include a plan for developing a strong research team, as well as a strategy to collect preliminary data linking putative therapeutic targets to the proposed pain indication and supporting the hypothesis that altering target activity will produce desirable outcomes for the disease.

https://www.grants.gov/web/grants/view-opportunity.html?oppId=334053

Department of Health and Human Services – National Institutes of Health – NIDA Animal Genomics Program (UO1 Clinical Trial Not Allowed)

Letter of Intent Due Date:                                              30 days prior to application due date

Proposal Due Date:                                                           July 26, 2021

Expected Number of Awards:

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Funding Opportunity Number:                                      PAR-21-244

Purpose: The purpose of the NIDA Animal Genetics Program is to identify genetic, genomic, and molecular (epi)genetic variants that underlie: 1. Phenotypes associated with addictive behaviors and/or vulnerability to distinct stages along the substance use disorder (SUD) trajectory (e.g. initial/acute use, escalation of use, acquisition of tolerance, dependence, uncontrolled use, abstinence and relapse or recovery); 2. Behaviors associated with SUD (e.g. impulsivity, novelty seeking, delayed discounting, and other genetically-associated phenotypes); and 3. Comorbidities that demonstrate genetic correlations with phenotypes and behaviors linked with SUD (e.g. anxiety, stress, poor maternal care, social defeat, and other paradigms). Applications may examine any type of variant, including single nucleotide variants (SNVs), indels, large and small structural variants, and all types of mobile DNA. NIDA encourages applications that take genomics, multi-omics, and/or data-based approaches that integrate multi-level omics data, delineate gene networks, and/or uncover the function of known or newly discovered genetic or epigenetic variants. NIDA expects these studies to uncover novel mechanisms that contribute to SUD and facilitate the discovery of targets for intervention and guide the development of individualized therapeutics to treat these different aspects of SUD.

https://www.grants.gov/web/grants/view-opportunity.html?oppId=334096

Department of Health and Human Services – National Institutes of Health – Integration, Dissemination, and Evaluation (BRIDGE) Center for the NIH Bridge to Artificial Intelligence (Bridge2AI) Program

Letter of Intent Due Date:                                              30 days prior to application due date

Proposal Due Date:                                                           August 20, 2021

Expected Number of Awards:

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Funding Opportunity Number:                                       RFA-RM-21-023

Purpose:  This Funding Opportunity Announcement (FOA) is associated with the NIH Common Fund Bridge2AI Program which seeks to generate flagship data sets and best practices for the collection and preparation of AI/ML-ready data to address biomedical and behavioral research grand challenges. The purpose of this FOA is to support an integration, dissemination and evaluation center which will integrate activities across Bridge2AI Data Generation Projects to develop cross-cutting products and best-practices.  This FOA invites cooperative agreement applications to develop a BRIDGE Center that will be responsible for integrating activities and knowledge across Data Generation Projects, disseminating products, best-practices, and skill development materials/activities, and evaluating all aspects of the Bridge2AI program with input from external stakeholder communities. The BRIDGE Center will combine cores of expertise in administration, team science, ethics, standards, tools optimization, and skills and workforce development.

https://www.grants.gov/web/grants/view-opportunity.html?oppId=334055

Department of Health and Human Services – National Institutes of Health – NIA Research and Entrepreneurial Development Immersion (REDI): Mentored Entrepreneurial Career Development Award (K01 Clinical Trial Not Allowed)

Proposal Due Date:                                                           September 29, 2021

Expected Number of Awards:

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Funding Opportunity Number:                                      RFA-AG-22-004

Purpose: The purpose of the NIA Research and Entrepreneurial Development Immersion (REDI): Mentored Entrepreneurial Career Development Award is to provide support and protected time (three to five years) for an intensive, supervised career development experience in the biomedical, behavioral, or clinical sciences leading to research independence.

https://www.grants.gov/web/grants/view-opportunity.html?oppId=334099

Department of Health and Human Services – National Institutes of Health – NIA Research and Entrepreneurial Development Immersion (REDI): Entrepreneurship Enhancement Award (R25 Clinical Trial Not Allowed)

Letter of Intent Due Date:                                              September 4, 2021

Proposal Due Date:                                                           October 4, 2021

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Funding Opportunity Number:                                      RFA-AG-22-003

Purpose: The purpose of the Research and Entrepreneurial Development Immersion (REDI): NIA Entrepreneurship Enhancement Award (R25) is to promote the development of entrepreneurial training programs that are designed to broaden the skillset of graduate students and postdocs, as well as early career master’s, Ph.D., and Dr.P.H. scientists, in fields relevant to the mission of NIA, including aging and Alzheimer’s disease (AD) research. The goal of this program is to prepare trainees for a wide range of career paths, including those that are outside the normal research environment.

https://www.grants.gov/web/grants/view-opportunity.html?oppId=334110  

Department of Health and Human Services – National Institutes of Health – Promoting Bunyaviral Basic Science Research (R01 Clinical Trial Not Allowed)

Letter of Intent Due Date:                                              30 days prior to the application due date

Proposal Due Date:                                                          October 22, 2021

Expected Number of Awards:

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Funding Opportunity Number:                                      RFA-AG-21-046

Purpose: The purpose of this Funding Opportunity Announcement (FOA) is to stimulate fundamental research of human disease-causing pathogens in the Bunyaviral order by supporting projects studying vector competence, virology, pathogenesis, and immunity.

https://www.grants.gov/web/grants/view-opportunity.html?oppId=334102

Department of Health and Human Services – National Institutes of Health – NIA Research and Entrepreneurial Development Immersion (REDI): Entrepreneurial Small business Transition Award (R43/R44 Clinical Trial Optional)

Letter of Intent Due Date:                                              September 26, 2021

Proposal Due Date:                                                          October 26, 2021

Expected Number of Awards:

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Funding Opportunity Number:                                     RFA-AG-22-007

Purpose: The goal of this Research and Entrepreneurial Development Immersion (REDI) Small Business Innovation Research (SBIR) Grant is to foster the career development of early-career scientists with an interest in entrepreneurship by simultaneously supporting their entrepreneurial development and facilitating their transition to industry.

https://www.grants.gov/web/grants/view-opportunity.html?oppId=334098

Department of Health and Human Services – National Institutes of Health – NIA Research and Entrepreneurial Development Immersion (REDI): Entrepreneurial Small Business Transition Award (R41/R42 Clinical Trial Optional)

Letter of Intent Due Date:                                              September 26, 2021

Proposal Due Date:                                                           October 26, 2021

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Funding Opportunity Number:                                     RFA-AG-22-014

Purpose: The goal of this Research and Entrepreneurial Development Immersion (REDI) Small Business Technology Transfer Research (STTR) Grant is to foster the career development of early career scientists with an interest in entrepreneurship by simultaneously supporting their entrepreneurial development and facilitating their transition to industry.

https://www.grants.gov/web/grants/view-opportunity.html?oppId=334097

Department of Health and Human Services – National Institutes of Health – High Resolution Mapping of Biomolecules in Brain Cells in Aging and Alzheimer’s Disease (R01 Clinical Trials Not Allowed)

Proposal Due Date:                                                           October 28, 2021

Expected Number of Awards:

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Award Ceiling:                                                                    $500,000

Award Floor:

Funding Opportunity Number:                                     RFA-AG-22-019

Purpose: This Funding Opportunity Announcement (FOA) will use the R01 funding mechanism to support discrete, specified, and circumscribed projects on novel molecular imaging approaches to establish high-resolution mapping of biomolecules in brain cells and regions during the course of aging and Alzheimer’s disease (AD).

https://www.grants.gov/web/grants/view-opportunity.html?oppId=334101

Department of Health and Human Services – National Institutes of Health – BRAIN Initiative: New Technologies and Novel Approaches for Recording and Modulation in the Nervous System (R01 Clinical Trial Not Allowed)

Letter of Intent Due Date:                                              60 days prior to application due date

Proposal Due Date:                                                           October 29, 2021

Expected Number of Awards:

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Funding Opportunity Number:                                      RFA-NS-21-026

Purpose:  Reissue of RFA-NS-18-020: Understanding the dynamic activity of brain circuits is central to the NIH BRAIN Initiative.  This FOA seeks applications for proof-of-concept testing and development of new technologies and novel approaches for recording and modulation (including various modalities for stimulation/activation, inhibition and manipulation) of cells (i.e., neuronal and non-neuronal) and networks to enable transformative understanding of dynamic signaling in the central nervous system (CNS).  This FOA seeks exceptionally creative approaches to address major challenges associated with recording and modulating CNS activity, at or near cellular resolution, at multiple spatial and/or temporal scales, in any region and throughout the entire depth of the brain.  It is expected that the proposed research may be high-risk, but if successful, could profoundly change the course of neuroscience research.  Proposed technologies should be compatible with experiments in behaving animals, validated under in vivo experimental conditions, and capable of reducing major barriers to conducting neurobiological experiments and making new discoveries about the CNS.  Technologies may engage diverse types of signaling beyond neuronal electrical activity such as optical, magnetic, acoustic and/or genetic recording/manipulation.  Applications that seek to integrate multiple approaches are encouraged.  If suitable, applications are expected to integrate appropriate domains of expertise, including biological, chemical and physical sciences, engineering, computational modeling and statistical analysis.

https://www.grants.gov/web/grants/view-opportunity.html?oppId=334067

Department of Health and Human Services – National Institutes of Health – BRAIN Initiative: Optimization of Transformative Technologies for Recording and Modulation in the Nervous System

Letter of Intent Due Date:                                              60 days prior to application due date

Proposal Due Date:                                                           October 29, 2021

Expected Number of Awards:

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Funding Opportunity Number:                                      RFA-NS-21-027

Purpose: Reissue of RFA-NS-18-019: Understanding the dynamic activity of neural circuits is central to the NIH BRAIN Initiative. The invention, proof-of-concept investigation, and optimization of new technologies through iterative feedback from end users are key components of the BRAIN Initiative. This FOA seeks applications to optimize existing or emerging technologies through iterative testing with end users. The technologies and approaches should have potential to address major challenges associated with recording and modulation (including various modalities for stimulation/activation, inhibition and manipulation) of cells (i.e., neuronal and non-neuronal) and networks to enable transformative understanding of dynamic signaling in the central nervous system (CNS).  These technologies and approaches should have previously demonstrated their transformative potential through initial proof-of-concept testing and are now ready for accelerated refinement. In conjunction, the manufacturing techniques should be scalable towards sustainable, broad dissemination and user-friendly incorporation into regular neuroscience research. Proposed technologies should be compatible with experiments in behaving animals, validated under in vivo experimental conditions, and capable of reducing major barriers to conducting neurobiological experiments and making new discoveries about the CNS.  Technologies may engage diverse types of signaling beyond neuronal electrical activity such as optical, electrical, magnetic, acoustic or genetic recording/manipulation.  Applications that seek to integrate multiple approaches are encouraged.  If suitable, applications are expected to integrate appropriate domains of expertise, including biological, chemical and physical sciences, engineering, computational modeling and statistical analysis.

https://www.grants.gov/web/grants/view-opportunity.html?oppId=334068