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DHHS Funding Opportunities

FUNDING OPPORTUNITIES from the Department of Health and Human Services (DHHS)       _______________________________________________________________

Department of Health and Human Services – Centers for Disease Control and Prevention – ERA – Characterizing the Natural History of Fragile X Syndrome to Inform the Development of Intervention Outcome Measures

Proposal Due Date: January 11, 2021

Expected Number of Awards: 1

Estimated Total Program Funding: $4,000,000

Award Ceiling: $800,000

Award Floor:

Funding Opportunity Number: RFA-DD-21-002

Purpose: The purpose of this NOFO is to conduct research to better characterize the natural history of fragile X syndrome (FXS) and meaningful outcome measures in order to improve the lives of children and adolescents with FXS with and without autism spectrum disorder (ASD). The funding will support enrollment and in-person standardized assessments of individuals aged 6 through 19 years with full-mutation FXS, which can include new and previously enrolled study participants of the Fragile X Online Registry with Accessible Research Database (FORWARD). FORWARD is a national registry of patients enrolled in FXS specialty clinics who are part of the Fragile X Clinical and Research Consortium. Data collection will include assessments to characterize the cognitive, behavioral, and adaptive skills, and other indicators of functioning of individuals with FXS. Planned coordination of standardized in-person behavioral and functional assessments and follow-up telephone survey questionnaires with CDC’s Study to Explore Early Development (SEED) Follow-up Study (RFA-DD21-001) will facilitate comparison of health and functional outcomes for the FXS population with those for other related and frequently co-occurring conditions such as ASD and developmental delay. Applicants may propose recruiting study participants from an individual FORWARD clinic, or recruiting from a group of FORWARD clinics with which the principal investigator has documented data sharing and collaborative agreements.

View more details on this opportunity.

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Department of Health and Human Services – Centers for Disease Control and Prevention – ERA – Advancing Public Health Research in Kenya

Proposal Due Date: February 15, 2020

Expected Number of Awards: 1

Estimated Total Program Funding: $75,000,000

Award Ceiling: $15,000,000

Award Floor:

Funding Opportunity Number: RFA-GH-21-003

Purpose: The purpose of this notice of funding opportunity is to conduct epidemiologic, clinical, laboratory, and operations research on infectious diseases, non-communicable diseases, and environmental health in Kenya in order to better understand disease burden, risk factors, and effective interventions to influence policy and decrease morbidity and mortality. Through this notice of funding opportunity, the Center for Global Health also seeks to build capacity to improve the quality of research in Kenya.

View more details on this opportunity.

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Department of Health and Human Services – Centers for Disease Control and Prevention – ERA – Conducting Research to Inform Pandemic Response and Recovery of Emergency-Affected Populations by Determining Public Health Needs, Improving Methods, and Integrating Services to Mitigate Morbidity and Mortality

Proposal Due Date: February 18, 2021

Expected Number of Awards: 5

Estimated Total Program Funding: $75,000,000

Award Ceiling: $3,000,000

Award Floor:

Funding Opportunity Number: RFA-GH-21-004

Purpose: The purpose of this notice of funding opportunity is to understand the needs of emergency-affected and displaced populations by improving epidemiological methods, estimating morbidity and mortality of these populations during COVID-19, as well as understand  the specific health sector needs of persons affected by humanitarian /public health emergencies and best practices for improving health outcomes.

Given the stress on surveillance systems and hypothesized secondary health effects on displaced populations and populations in humanitarian emergency settings, this NOFO requests applicants to submit applications proposing research studies among populations in humanitarian settings (such as refugee camps and internally displaced populations) in order to do at least one of the following:

  1. Improve mortality estimation and cause of death methods in the acute emergency phase.
  2. Understand SARS-CoV-2 transmission among displaced populations by comparing surveillance strategies and develop an understanding of risk factors, and motivators and barriers for certain mitigation measures.
  3. Study the effects of hand hygiene interventions on mitigating the spread of COVID-19.
  4. Understand COVID-19 secondary health impacts among displaced persons.
  5. Understand the impact of COVID-19 on mental health.

View more details on this opportunity.

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Department of Health and Human Services – Centers for Disease Control and Prevention – ERA – Identify and Evaluate Potential Risk Factors for Amyotrophic Lateral Sclerosis (ALS)

Proposal Due Date: February 26, 2021

Expected Number of Awards: 5

Estimated Total Program Funding: $75,000,000

Award Ceiling: $500,000

Award Floor:

Funding Opportunity Number: RFA-TS-21-001

Purpose: The Agency for Toxic Substances and Disease Registry (ATSDR) is soliciting investigator initiated research that will further the understanding of potential risk factors for ALS, while supporting the National ALS Registry’s mission. The National ALS Registry’s goals are to estimate the number of new ALS cases each year, estimate the number of people who have ALS at a specific point in time, better understand who gets ALS, and identify what contributing factors, including environmental, may affect ALS. ATSDR is seeking investigator-initiated research that will identify and evaluate risk factors contributing to ALS, with preferred focus in this Notice of Funding Opportunity on factors related to military service, contact sports, traumatic brain injury, neuroinflammation and infectious agents.

View more details on this opportunity.

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Department of Health and Human Services – Health Resources and Services Administration – Ryan White HIV/AIDS Program Part D — Women, Infants, Children, and Youth (WICY) Grants Supplemental Funding

Proposal Due Date: January 12, 2021

Expected Number of Awards: 25

Estimated Total Program Funding: $3,000,000

Award Ceiling:

Award Floor:

Funding Opportunity Number: HRSA-21-059

Purpose: This notice announces the opportunity to apply for funding under the Ryan White HIV/AIDS Program (RWHAP) Part D Women, Infants, Children, and Youth (WICY) (RWHAP Part D WICY or RWHAP Part D) Grants Supplemental Funding for fiscal year (FY) 2021.

The purpose of this supplemental funding is to strengthen organizational capacity to respond to the changing health care landscape and increase access to high quality, family-centered HIV primary health care services for low income, uninsured, and underserved WICY with HIV.

HRSA intends funding under this program to support one short-term activity that can be completed by the end of the one-year period of performance. You may propose an expansion of an activity previously supported under FY2019 or FY2020 RWHAP Part D Supplemental (HRSA-19-026; HRSA-20-068) or Part C Capacity Development funding (HRSA-19-031; HRSA-20-067) for either an HIV Care Innovation or Infrastructure Development activity; however, HRSA will not fund the same activity in FY 2021 as HRSA funded previously in FY2019 or FY2020. If the proposed project is an expansion of a previously funded activity, you must provide a clear rationale for how the proposed activity builds upon and furthers the objectives of the previously funded HIV Care Innovation or Infrastructure Development activity. You may select only one (1) activity under the selected category.

HIV Care Innovation

HIV Care Innovation activities support progress along the HIV care continuum to improve the health and increase the life span of people with HIV, and prevent new infections. There are five (5) activities from which to choose. If applying under this category, select only one of the five activities listed below:

Infrastructure Development

Infrastructure Development activities support organizational development and will increase the capacity of organizations to respond to changes in the health care environment. There is only one activity to choose.

Telemedicine

Collectively, activities will allow RWHAP Part D programs to better align with priority areas for the Department of Health and Human Services (HHS) and the Health

Resources and Services Administration (HRSA), including investing in addressing the opioid crisis, mental health, and promoting collaboration. The selected activity should target populations that are disproportionately impacted by the HIV epidemic and experience adverse health outcomes. Successful applicants will demonstrate your organization’s intent and ability to sustain proposed HIV Care Innovation activities or proposed Infrastructure Development enhancements without additional federal funds beyond the one-year period of performance. Furthermore, successful applicants will demonstrate that the proposed activity will strengthen organizational capacity to respond to the changing health care landscape and increase access to high-quality HIV primary health care services for low income, uninsured, and underserved people with HIV.

View more details on this opportunity.

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Department of Health and Human Services – Health Resources and Services Administration – UT5 Developmental Behavioral Pediatrics Research Network (DBPNet)

Proposal Due Date: February 2, 2021

Expected Number of Awards: 1

Estimated Total Program Funding: $275,000

Award Ceiling: $275,000

Award Floor:

Funding Opportunity Number: HRSA-21-039

Purpose: This notice announces the opportunity to apply for funding under the UT5 Developmental Behavioral Pediatrics Research Network (DBPNet) Program. The purpose of this program is to establish and maintain a national, multi-site, collaborative research network for scientific collaboration and infrastructure building. This Research Network will provide national leadership in research to advance the evidence base in the developmental, behavioral, and psychosocial aspects of pediatric care to improve clinical services and health and related outcomes for children and adolescents with autism spectrum disorder and other developmental disabilities (ASD/DD) across the lifespan. It will work to develop effective interventions1 in clinical services and to improve health and related outcomes for children and adolescents with autism spectrum disorder and other developmental disabilities (ASD/DD).

The Research Network will:

For cooperative agreement activities, please see Project Narrative Section III.

View more details on this opportunity.

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Department of Health and Human Services – National Institutes of Health – Promoting Viral Suppression among Individuals from Health Disparity Populations Engaged in HIV Care (R01 Clinical Trial Required)

Letter of Intent Due Date: December 15, 2020

Proposal Due Date: January 15, 2021

Expected Number of Awards:

Estimated Total Program Funding:

Award Ceiling: $500,000

Award Floor:

Funding Opportunity Number: RFA-MD-21-002

Purpose: The objective of this initiative is to further knowledge about “treatment as prevention” strategies to reduce the number of new HIV infections in the US. This initiative will support research projects to test interventions to promote antiretroviral therapy (ART) initiation, ART adherence, and suppressed viral load for people living with HIV (PLWH) from health disparity populations who live in geographic areas with a high rate of new HIV infections and are engaged in HIV care.

View more details on this opportunity.

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Department of Health and Human Services – National Institutes of Health – Multi-Level HIV Prevention Interventions for Individuals at the Highest Risk of HIV Infection (R01 Clinical Trial Optional)

Letter of Intent Due Date: December 15, 2020

Proposal Due Date: January 15, 2021

Expected Number of Awards:

Estimated Total Program Funding:

Award Ceiling:

Award Floor:

Funding Opportunity Number: RFA-MD-21-001

Purpose: This initiative will support R01 projects that test the effectiveness of multi-level interventions to prevent HIV in high-risk health disparity populations or subgroups in one or more geographic areas with a high rate of new infections.

View more details on this opportunity.

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Department of Health and Human Services – National Institutes of Health – Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Basic Experimental Studies with Humans Required)

Proposal Due Date: January 26, 2021

Expected Number of Awards:

Estimated Total Program Funding:

Award Ceiling:

Award Floor:

Funding Opportunity Number: PAR-21-039

Purpose: The Stephen I. Katz Early Stage Investigator Research Project Grant supports an innovative project that represents a change in research direction for an early stage investigator (ESI) and for which no preliminary data exist. Applications submitted to this Funding Opportunity Announcement (FOA) must not include preliminary data. Applications must include a separate attachment describing the change in research direction. The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions.

This Funding Opportunity Announcement is for basic science experimental studies involving humans, referred to in NOT-OD-18-212 as “prospective basic science studies involving human participants.” These studies fall within the NIH definition of a clinical trial and also meet the definition of basic research. Types of studies that should submit under this FOA include studies that prospectively assign human participants to conditions (i.e., experimentally manipulate independent variables) and that assess biomedical or behavioral outcomes in humans for the purpose of understanding the fundamental aspects of phenomena without specific application towards processes or products in mind. Studies that are NOT conducted with specific applications toward processes or products in mind and which also do not meet the clinical trial definition should submit under the appropriate ‘Clinical Trial Not Allowed’ FOA.

View more details on this opportunity.

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Department of Health and Human Services – National Institutes of Health – Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed)

Proposal Due Date: January 26, 2021

Expected Number of Awards:

Estimated Total Program Funding:

Award Ceiling:

Award Floor:

Funding Opportunity Number: PAR-21-038

Purpose: The Stephen I. Katz Early Stage Investigator Research Project Grant supports an innovative project that represents a change in research direction for an early stage investigator (ESI) and for which no preliminary data exist. Applications submitted to this Funding Opportunity Announcement (FOA) may not include preliminary data. The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions. This Funding Opportunity Announcement does not accept applications proposing clinical trials.

View more details on this opportunity.

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Department of Health and Human Services – National Institutes of Health – Limited Competition: Lasker Clinical Research Scholars Transition Award (R00 Clinical Trial Optional)

Proposal Due Date: Rolling receipt dates: December 6, 2020 – January 31, 2021; February 1, 2021 – May 31, 2021; June 1, 2021 – September 30, 2021; October 1, 2021 – January 31, 2022; February 1, 2022 – May 31, 2022; June 1, 2022 – September 30, 2022; October 1, 2022- January 31, 2023; February 1, 2023 – May 31, 2023; June 1, 2023 – September 30, 2023

Expected Number of Awards:

Estimated Total Program Funding:

Award Ceiling:

Award Floor:

Funding Opportunity Number: PAR-20-315

Purpose: The Lasker Clinical Research Scholars Program supports research activities during the early stage careers of independent clinical researchers.  This FOA offers the opportunity for current Lasker awardees (Si2) to apply for the transition phase (R00) of the program.  In the R00 phase, successful Si2 scholars will receive up to 5 years of NIH support for their research at an extramural research facility.

View more details on this opportunity.

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Department of Health and Human Services – National Institutes of Health – Pilot Projects Enhancing Utility and Usage of Common Fund Data Sets (R03 Clinical Trial Not Allowed)

Letter of Intent Due Date: 30 days prior to application due date

Proposal Due Date: February 19, 2021

Expected Number of Awards:

Estimated Total Program Funding:

Award Ceiling:

Award Floor:

Funding Opportunity Number: RFA-RM-21-007

Purpose: Several valuable and widely available data sets have been generated by multiple Common Fund programs. The purpose of this funding opportunity announcement (FOA) is to announce the availability of funding to demonstrate and enhance the utility of selected Common Fund data sets, including generating hypotheses and catalyzing discoveries. Award recipients are also asked to provide feedback on the utility of the Common Fund data resources.

View more details on this opportunity.

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Department of Health and Human Services – Substance Abuse and Mental Health Services Administration – Statewide Consumer Network Program

Proposal Due Date: January 4, 2021

Expected Number of Awards: 12

Estimated Total Program Funding: $1,200,000

Award Ceiling: $950,000

Award Floor:

Funding Opportunity Number: SM-21-001

Purpose: The Substance Abuse and Mental Health Services Administration (SAMHSA), Center for Mental Health Services (CMHS) is accepting applications for fiscal year (FY) 2021 Statewide Consumer Network grant program (Short Title: SCN). The purpose of this program is to improve efforts to address the needs of adults with serious mental illness (SMI) by developing and/or expanding peer support services, peer leadership, and peer engagement strategies statewide. The population of focus is adults with SMI, including those who are underserved and under-represented (e.g., consumers from ethnic, racial, and cultural minority groups); veterans; individuals who are chronically homeless; individuals with co-occurring disorders (COD); sexual orientation and gender identity minorities; and individuals who have been involved in the criminal justice system. It is expected that this program will increase access to and quality of mental health services for adults with SMI; increase the sustainability of consumer-operated organizations; and enhance state capacity and infrastructure to support the recovery of adults with SMI and their families.

View more details on this opportunity.

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Department of Health and Human Services – Substance Abuse and Mental Health Services Administration – Statewide Family Network

Proposal Due Date: January 4, 2021

Expected Number of Awards: 10

Estimated Total Program Funding: $950,000

Award Ceiling: $950,000

Award Floor:

Funding Opportunity Number: SM-21-002

Purpose: The Substance Abuse and Mental Health Services Administration (SAMHSA), Center for Mental Health Services (CMHS) is accepting applications for fiscal year (FY) 2021 Statewide Family Network grant program (Short Title: SFN). The purpose of this program is to more effectively respond to the needs of children, youth, and young adults with serious emotional disturbances (SED) and their families by providing information, referrals, and support; and to create a mechanism for families to participate in state and local mental health services planning and policy development. This population of focus will hereafter be referred to as children and youth. SAMHSA expects that this program will be a catalyst for transforming mental health and related systems in the state by strengthening coalitions among family organizations and between family members, policy makers, and service providers.

View more details on this opportunity.