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DHHS Funding Opportunities

FUNDING OPPORTUNITIES from the Department of Health and Human Services (DHHS)

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Department of Health and Human Services – Health Resources and Services Administration – Ryan White HIV/AIDS Program Part C Capacity Development Program

Proposal Due Date: February 19, 2021

Expected Number of Awards: 60

Estimated Total Program Funding: $8,000,000

Award Ceiling:

Award Floor:

Funding Opportunity Number: HRSA-21-058

Purpose: This notice announces the opportunity to apply for funding under the Health Resources and Services Administration’s (HRSA) Ryan White HIV/AIDS Program (RWHAP) Part C Capacity Development Program. The purpose of this program is to strengthen organizational capacity to respond to the changing health care landscape and increase access to high-quality HIV primary health care services for low-income, uninsured, and underserved people with HIV.

Funding under this program is intended to support one short-term activity that can be completed by the end of the one-year period of performance. You may propose an expansion of an activity previously supported under FY2019 or FY2020 RWHAP Part D Supplemental (HRSA-19-026; HRSA-20-068) or Part C Capacity Development funding (HRSA-19-031; HRSA-20-067) however, HRSA will not fund the same activity in FY 2021 as HRSA funded previously in FY 2019 or FY 2020. If the proposed project is an expansion of a previously funded activity, you will be required to provide a clear rationale for how the proposed activity builds upon and furthers the objectives of the previously funded HIV Care Innovation or Infrastructure Development activity.

View more details on this opportunity.

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Department of Health and Human Services – Centers for Disease Control and Prevention – Collaborative Research on Influenza, Coronavirus Disease 2019 (COVID-19), and Other Respiratory Pathogens in South Africa 

Proposal Due Date: March 9, 2021

Expected Number of Awards: 1

Estimated Total Program Funding: $3,750,000

Award Ceiling: $1,250,000

Award Floor: $1,000,000

Funding Opportunity Number: RFA-IP-21-003

Purpose: The purpose of this Notice of Funding Opportunity (NOFO) is to conduct research studies on influenza, coronavirus disease 2019 (COVID-19), and other respiratory pathogens in South Africa. The National Center for Immunization and Respiratory Diseases (NCIRD) and the Center for Global Heath (CGH) are seeking to initiate a cooperative agreement with the National Institute for Communicable Diseases (NICD), Republic of South Africa, to conduct studies on the epidemiology, disease burden, transmission, risk factors for hospitalization and death from respiratory viral diseases, especially influenza and COVID-19. Data will be used to inform prioritization of public health interventions in high risk populations in South Africa.

View more details on this opportunity. 

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Department of Health and Human Services – Centers for Disease Control and Prevention – Grants to Support New Investigators in Conducting Research Related to Preventing Interpersonal Violence Impacting Children and Youth

Proposal Due Date: March 10, 2021

Expected Number of Awards: 2

Estimated Total Program Funding: $500,000

Award Ceiling: $125,000

Award Floor: $100,000

Funding Opportunity Number: RFA-CE-21-003

Purpose: The purpose of the Centers for Disease Control and Prevention National Center for Injury Prevention and Control (NCIPC) Mentored Research Scientist Development Award (K01) is to provide support for an intensive, supervised (mentored) career development experience in violence prevention research leading to research independence. NCIPC supports K01 grants to help ensure the availability of an adequate number of trained scientists to address critical public health research questions to prevent violence and injury.

Applicants must propose a research project that addresses at least one of the research priorities in the interpersonal violence prevention section of the NCIPC Research Priorities (https://www.cdc.gov/injury/researchpriorities/index.html) as they relate to violence impacting children or youth (from birth through age 17). These research priorities include:

View more details on this opportunity.

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Department of Health and Human Services – Centers for Disease Control and Prevention – Research Grants for Preventing Violence and Violence Related Injury (R01)

Proposal Due Date: March 22, 2021

Expected Number of Awards: 3

Estimated Total Program Funding: $3,150,000

Award Ceiling: $350,000

Award Floor:

Funding Opportunity Number: RFA-CE-21-004

Purpose: The Centers for Disease Control and Prevention’s National Center for Injury Prevention and Control (NCIPC) is soliciting investigator-initiated research that will help expand and advance our understanding about what works to prevent violence that impacts children and youth, collectively referred to as Adverse Childhood Experiences (ACEs), including child abuse and neglect, teen dating violence, sexual violence, youth violence, and exposure to adult intimate partner violence. This initiative is intended to support the evaluation of primary prevention programs, practices or policies that focus on universal or selected populations at higher risk (i.e., populations that have one or more risk factors that place them at heightened risk for violence). Funds are available to conduct such studies focused on preventing child abuse and neglect and at least one other form of violence affecting children and youth, including teen dating violence, sexual violence, youth violence, and exposure to adult intimate partner violence.

View more details on this opportunity.

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Department of Health and Human Services – Centers for Disease Control and Prevention – Developing and Disseminating Targeted Immunization Materials

Proposal Due Date: April 15, 2021

Expected Number of Awards: 1

Estimated Total Program Funding: $1,750,000

Award Ceiling:

Award Floor:

Funding Opportunity Number: CDC-RFA-IP21-2104

Purpose: The purpose of the Notice of Funding Opportunity is to provide support for the development and dissemination of immunization information through electronic formats to enhance the effectiveness of disease prevention programs that reduce the annual burden of vaccine-preventable diseases. The recipient will: (1) develop educational materials for providers to share with patients, parents, and the general public; (2) disseminate educational materials on current immunization recommendations and practices to providers and other partners; (3) develop training opportunities and provide technical assistance for coalitions; and (4) provide rapid-response communication on outbreaks, emergency response, or trending immunization priorities.

View more details on this opportunity.

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Department of Health and Human Services – Health Resources and Services Administration – Maternal and Child Health Workforce Development Center Program

Proposal Due Date: April 6, 2021

Expected Number of Awards: 1

Estimated Total Program Funding: $1,970,000

Award Ceiling:

Award Floor:

Funding Opportunity Number: HRSA-21-043

Purpose: This notice announces the opportunity to apply for funding under the Maternal and Child Health (MCH) Workforce Development Center Program (the Center). The purpose of the program is to strengthen the practicing and future MCH workforce by providing training and collaborative learning for State Title V Maternal and Child Health Services Block Grant Program leaders and staff. Training will focus on three key topic areas related to health transformation1, including ongoing implementation of the Title V Block Grant: (1) systems integration; (2) change management and adaptive leadership; and (3) evidence-based decision making. The objectives of the program are to (1) coordinate and implement a national training strategy to address all three key topic areas within the Center’s purview; (2) develop and offer multiple modalities of training to Title V leaders and staff, emphasizing project-based, collaborative learning for cross-sector state teams and real-time application of knowledge and skills in an MCH context; (3) support summer practicum/internship placements for the future Title V workforce (undergraduate and graduate students); and (4) establish and strengthen academic-practice partnerships with state Title V Programs and national public health practice partners. Also in this notice is the opportunity to apply for additional funding to support Building Capacity to Advance Population Health Approaches for Children and Youth with Special Health Care Needs (CYSHCN). Applying for additional funding to support Building Capacity to Advance Population Health Approaches for CYSHCN is optional.

View more details on this opportunity.

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Department of Health and Human Services – Substance Abuse and Mental Health Services Administration – Certified Community Behavioral Health Clinic Expansion Grants

Proposal Due Date: March 1, 2021

Expected Number of Awards: 74

Estimated Total Program Funding: $149,000,000

Award Ceiling: $2,000,000

Award Floor:

Funding Opportunity Number: SM-21-013

Purpose: The Substance Abuse and Mental Health Services Administration (SAMHSA), Center for Mental Health Services (CMHS) is accepting applications for fiscal year (FY) 2021 Certified Community Behavioral Health Clinics (CCBHCs) Expansion Grants (Short Title: CCBHC Expansion Grants). The purpose of this program is to increase access to, and improve the quality of community mental and substance use disorder treatment services through the expansion of CCBHCs. CCBHCs provide person- and family-centered integrated services. The CCBHC Expansion grant program must provide access to services including 24/7 crisis intervention services for individuals with serious mental illness (SMI) or substance use disorders (SUD), including opioid use disorders; children and adolescents with serious emotional disturbance (SED); and individuals with co-occurring mental and substance disorders (COD). SAMHSA expects that this program will provide comprehensive 24/7 access to community-based mental and substance use disorder services; treatment of co-occurring disorders; and physical healthcare in one single location.

View more details on this opportunity.

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Department of Health and Human Services – Substance Abuse and Mental Health Services Administration – Grants to Prevent Prescription Drug/Opioid Overdose-Related Deaths

Proposal Due Date: March 1, 2021

Expected Number of Awards: 13

Estimated Total Program Funding: $11,397,000

Award Ceiling: $850,000

Award Floor:

Funding Opportunity Number: SP-21-002

Purpose: The Substance Abuse and Mental Health Services Administration (SAMHSA), Center for Substance Abuse Treatment (CSAT), is accepting applications for fiscal year (FY) 2021 Grants to Prevent Prescription Drug/Opioid Overdose-Related Deaths (Short title: PDO). The purpose of this program is to reduce the number of prescription drug/opioid overdose-related deaths and adverse events among individuals 18 years of age and older by training first responders and other key community sectors on the prevention of prescription drug/opioid overdose-related deaths and implementing secondary prevention strategies, including the purchase and distribution of naloxone to first responders.

View more details on this opportunity.

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Department of Health and Human Services – National Institute of Health – Music and Health: Understanding and Developing Music Medicine (R21 Clinical Trial Optional)

Letter of Intent Due Date: January 16, 2021

Proposal Due Date: February 16, 2021

Expected Number of Awards:

Estimated Total Program Funding:

Award Ceiling: $200,000.00

Award Floor:

Funding Opportunity Number: PAR-21-099

Purpose: This FOA is intended to: (1) increase our understanding of how music affects the brain when it is used therapeutically and/or (2) use that knowledge to better develop evidence-based music interventions to enhance health or treat specific diseases and disorders.

View more details on this opportunity. ________________________________________________________

Department of Health and Human Services – National Institute of Health – Novel Approaches to Decrease Stigma of Substance Use Disorders in order to Facilitate Prevention, Treatment, and Support During Recovery (R41/R42 – Clinical Trial Optional)

Letter of Intent Due Date: January 26, 2021

Proposal Due Date: February 26, 2021

Expected Number of Awards:

Estimated Total Program Funding: $2,000,000

Award Ceiling: $256,580

Award Floor:

Funding Opportunity Number: RFA-DA-21-015

Purpose: The purpose of this Funding Opportunity Announcement is to support research applications for commercializable products aimed at reducing stigma around substance use disorders (SUD). Phase I applications are invited to develop and evaluate feasibility of novel digital technologies, services or other interventions to reduce stigma towards SUD in clinical care, including HIV prevention and care settings, clinical training and other relevant settings, and to establish methods to measure stigma reduction. Phase II applications are invited to demonstrate efficacy in decreasing stigma towards SUD and commercialization potential of these products in clinical care, training, and/or other relevant settings, including those providing HIV prevention and care with the goal to remove barriers to SUD prevention, treatment, and support during recovery. Phase II applications focused on HIV prevention and care settings are invited to demonstrate efficacy in decreasing stigma towards SUD and improving health outcomes for people living with HIV and SUD.

View more details on this opportunity.

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Department of Health and Human Services – National Institute of Health – Novel Approaches to Decrease Stigma of Substance Use Disorders in order to Facilitate Prevention, Treatment, and Support During Recovery (R43/R44 – Clinical Trial Optional)

Letter of Intent Due Date: January 26, 2021

Proposal Due Date: February 26, 2021

Expected Number of Awards:

Estimated Total Program Funding: $2,000,000

Award Ceiling: $256,580

Award Floor:

Funding Opportunity Number: RFA-DA-21-016

Purpose: The purpose of this Funding Opportunity Announcement is to support research applications for commercializable products aimed at reducing stigma around substance use disorders (SUD). Phase I applications are invited to develop and evaluate feasibility of novel digital technologies, services or other interventions to reduce stigma towards SUD in clinical care, including HIV prevention and care settings, clinical training and other relevant settings, and to establish methods to measure stigma reduction. Phase II applications are invited to demonstrate efficacy in decreasing stigma towards SUD and commercialization potential of these products in clinical care, training, and/or other relevant settings, including those providing HIV prevention and care with the goal to remove barriers to SUD prevention, treatment, and support during recovery. Phase II applications focused on HIV prevention and care settings are invited to demonstrate efficacy in decreasing stigma towards SUD and improving health outcomes for people living with HIV and SUD.

View more details on this opportunity.

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Department of Health and Human Services – National Institute of Health – Improving Health Disparities in Alcohol Health Services (R01 Clinical Trial Optional)

Letter of Intent Due Date: February, 15, 2021

Proposal Due Date: March 15, 2021

Expected Number of Awards:

Estimated Total Program Funding:

Award Ceiling: $500,000

Award Floor:

Funding Opportunity Number: RFA-AA-21-001

Purpose: The National Institute on Alcohol Abuse and Alcoholism intends to renew an initiative by publishing a Funding Opportunity Announcement (FOA) to solicit applications for an R01 Clinical Trial Optional mechanism focusing on health disparities and health services.  This FOA will include five areas of focus: access to treatment, making treatment more appealing, costs, dissemination and implementation, and health disparities.  Applications are expected to emphasize health disparities in addition to the other four areas of emphasis.

View more details on this opportunity.

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Department of Health and Human Services – Centers for Disease Control and Prevention – FY 21 Broad Agency Announcement

White Papers Due Date: January 13, 2021

Expected Number of Awards:

Estimated Total Program Funding:

Award Ceiling:

Award Floor:

Funding Opportunity Number: 75D301-21-R-71738

Purpose: The Centers for Disease Control and Prevention (CDC), the Office of Science (OS) issues this Broad Agency Announcement (BAA) under the provisions of FAR 35.016 and FAR 6.102(d)(2) which provides for the competitive selection of research proposals. Contracts that are awarded based on responses to this BAA are as a result of full and open competition and therefore in full compliance with the provisions of PL 98-369, “The Competition in Contracting Act of 1984.”

The CDC may award contracts with educational institutions, nonprofit organizations, not for profit organizations, state and local government, and private industry for research and development (R&D) in those areas covered in Part II of this BAA.

The Centers for Disease Control is issuing Broad Agency Announcement (BAA) Number 75D301-21-R-71738. The NAICS code for this BAA is 541715, Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology) with a size standard of 1,000 employees. This BAA is open and in effect for 28 days from the date of issuance (December 16, 2020 through January 13, 2021). THIS IS AN IMMEDIATE CALL FOR WHITE PAPERS. Prior to submission of a white paper, offerors are strongly encouraged to contact the CDC BAA technical point of contact for the research topic/subtopic of interest. White papers must be received electronically by 3:00 PM EST on January 13, 2021 in order to be considered for further evaluation. White papers should be submitted electronically to the mailbox at oadsbaaprojects@cdc.gov with a copy to the BAA Technical Coordinator, Diana Barlett at dbartlett@cdc.gov, and with a copy to Dr. Mim Kelly at Mkelly2@cdc.gov.

View more details on this opportunity.

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Department of Health and Human Services – Centers for Disease Control – CGH – Elimination of lymphatic filariasis and elimination and control of other neglected tropical diseases (NTDs) in an effort to improve the quality and coverage of local programs.

Proposal Due Date: February 19, 2021

Expected Number of Awards: 4

Estimated Total Program Funding: $3,450,000

Award Ceiling:

Award Floor:

Funding Opportunity Number: CDC-RFA-GH21-2104

Purpose: The purpose of this announcement is to support endemic countries in strengthening their program capacity for elimination/control of LF and other NTDs through achieving MDA coverage targets; establishing ongoing, systematic surveillance systems that can identify recrudescence of infection; establishing standard procedures for responding promptly to persistent or recrudescent transmission; and supporting integrated health services for LF and other NTDs within national health systems. For LF, measurable outcomes of the program will be: improved quality of, access to, and participation in MDA campaigns; better understanding of community participation (and non-participation) in MDAs by countries and other stakeholders; improved management of chronic disease in communities; identification of appropriate MDA stopping points and hotspot management; and establishment of feasible yet high-quality monitoring, evaluation and surveillance before, during and after MDAs. For other NTDs, measurable outcomes will be improved quality of MDAs; understanding of MDA starting and stopping points (e.g., onchocerciasis); high quality conduct of NTD monitoring, evaluation and surveillance, including post-elimination surveillance; and integration of NTD surveillance and services within existing health systems. This announcement is only for non-research activities supported by CDC. If research is proposed, the application will not be reviewed. For the definition of research, please see the CDC Web site at the following Internet address: http://www.cdc.gov/od/science/integrity/docs/cdc-policy-distinguishing-public-health-research-nonresearch.pdf.

View more details on this opportunity.

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Department of Health and Human Services – Centers for Disease Control – Health Promotion and Disease Prevention Research Centers: 2021 Special Interest Project Competitive Supplements (SIPS)

Proposal Due Date: February 25, 2021

Expected Number of Awards: 12

Estimated Total Program Funding: $9,080,000

Award Ceiling: $3,785,000

Award Floor:

Funding Opportunity Number: RFA-DP-21-004

Purpose: This Notice of Funding Opportunity (NOFO) will provide supplemental funding to Prevention Research Centers (PRCs), currently funded under CDC RFA-DP-19-001; to conduct Special Interest Projects (SIPs) to design, test, evaluate, disseminate and translate effective applied public health prevention research on interventions (i.e. programs, practices, policies, or strategies) and tools developed in real-world settings to address the leading causes of illness, disabilities, and death in the United States.  Research projects announced in this NOFO align with public health priorities associated with Healthy People 2030 topic areas: Adolescent Health, Arthritis, Cancer Prevention and Care, Drug and Alcohol Use, Maternal, Infant and Child Health, Mental Health and Mental Disorders, Physical Activity, and Health care access and quality.

View more details on this opportunity. ________________________________________________________

Department of Health and Human Services – Centers for Disease Control – Supporting and Improving the Chronic Kidney Disease Surveillance System in the United States

Proposal Due Date: March 1, 2021

Expected Number of Awards: 2

Estimated Total Program Funding: $6,000,000

Award Ceiling: $1,200,000

Award Floor: $600,000

Funding Opportunity Number: CDC-RFA-DP21-2107

Purpose: This award will build upon the previous CKD surveillance work to continue supporting, updating, and improving the CKD Surveillance System with relevant data sources and indicators and up-to-date data and trends, to enhance the CKD Surveillance System website with data updates, state-of-the-art technologies and visualization tools, and to assist CDC, prevention researchers, policy makers, medical practitioners, and states in developing and evaluating programs and policies to better prevent, detect, and manage CKD.

NOFO goals are to:• Support, update, and improve the CKD Surveillance System in the United States https://nccd.cdc.gov/CKD/ (Component A), and• Support, update, and enhance the currently functional and interactive website application of the CKD Surveillance System https://nccd.cdc.gov/CKD/ (Component B).

The recipients will have access to the current documentation and existing data in the system.

View more details on this opportunity. ________________________________________________________

Department of Health and Human Services – Health Resources and Services Administration – Service Area Competition

Proposal Due Date: February 16, 2021

Expected Number of Awards: 2

Estimated Total Program Funding: $2,436,291

Award Ceiling:

Award Floor:

Funding Opportunity Number: HRSA-21-008

Purpose: This notice announces the opportunity to apply for funding under the Health Center Program’s Service Area Competition (SAC). The Health Center Program supports public and private nonprofit community-based and patient-directed organizations that provide primary health care services to the Nation’s medically underserved populations. The purpose of the SAC notice of funding opportunity (NOFO) is to ensure continued access to comprehensive, culturally competent, quality primary health care services for communities and populations currently served by the Health Center Program.

View more details on this opportunity. ________________________________________________________

Department of Health and Human Services – Health Resources and Services Administration – Using Innovative Intervention Strategies to Improve Health Outcomes among People with HIV – Evaluation Center

Proposal Due Date: March 8, 2021

Expected Number of Awards: 1

Estimated Total Program Funding: $1,050,000

Award Ceiling:

Award Floor:

Funding Opportunity Number: HRSA-21-068

Purpose: This notice announces the opportunity to apply for fiscal year 2021 (FY21) Health Resources and Services Administration (HRSA) Special Projects of National Significance (SPNS) Program funding for the initiative Using Innovative Intervention Strategies to Improve Health Outcomes among People with HIV – Evaluation Center. The purpose of this initiative is to use an implementation science framework1 to evaluate the pilot testing of innovative intervention strategies in four (4) focus areas at implementation sites subawarded through the companion cooperative agreement Using Innovative Intervention Strategies to Improve Health Outcomes among People with HIV – Coordinating Center (2iS CCTA; HRSA-21-076), and to disseminate the evaluation findings. HRSA will provide funding in the form of a cooperative agreement to support one (1) organization for up to four (4) years to serve as the Innovative Intervention Strategies Evaluation Center (2iS EC). The 2iS EC will develop and carry out a multi-site evaluation that includes a customized site-specific evaluation for each of the up to twenty (20) Ryan White HIV/AIDS Program (RWHAP)-funded recipients/subrecipients (approximately five sites per focus area) to serve as implementation sites where one intervention strategy per site will be piloted. In addition to the site-specific components, the evaluation will include cross-site components (e.g., costing, organizational assessments) that are consistent across all subawardee sites. Throughout this initiative, the 2iS EC will work closely with the 2iS CCTA, which will provide technical assistance to the subawardees. Ultimately, the 2iS EC’s evaluation findings will determine dissemination plans for the replication tools developed by the 2iS CCTA. Please review the companion funding opportunity announcement for more information on the role of the 2iS CCTA (HRSA-21-076). You may also review the previous initiative for which this is a competing continuation (HRSA-17-044; HRSA-17-049). 2iS Focus Areas This recipient will evaluate the implementation and associated health outcomes of three (3) priority populations and one (1) area of opportunity to improve service delivery for people with HIV. Combined, these four (4) focus areas are: 1) Improving HIV health outcomes for people with substance use disorder 2) Improving HIV health outcomes for lesbian, gay, bisexual, transgender, or queer (LGBTQ+) youth 3) Improving HIV health outcomes for people who are or have been incarcerated 4) Improving HIV health outcomes by using telehealth services.

View more details on this opportunity. ________________________________________________________

Department of Health and Human Services – Health Resources and Services Administration – Using Innovative Intervention Strategies to Improve Health Outcomes among People with HIV – Evaluation Center

Proposal Due Date: March 8, 2021

Expected Number of Awards: 1

Estimated Total Program Funding: $4,825,000

Award Ceiling:

Award Floor:

Funding Opportunity Number: HRSA-21-076

Purpose: This notice announces the opportunity to apply for fiscal year 2021 (FY21) Health Resources and Services Administration (HRSA) Special Projects of National Significance (SPNS) Program funding for the initiative Using Innovative Intervention Strategies to Improve Health Outcomes among People with HIV – Coordinating Center. The purpose of this initiative is to use an implementation science framework1 to identify innovative intervention strategies in four (4) focus areas, pilot test the intervention strategies at subawarded sites and provide technical assistance (TA), and develop replication tools and products. HRSA will provide funding in the form of a cooperative agreement to support one (1) organization for up to four (4) years to serve as the Innovative Intervention Strategies Coordinating Center for Technical Assistance (2iS CCTA). The 2iS CCTA will solicit and subaward up to 20 Ryan White HIV/AIDS Program (RWHAP)-funded recipients/subrecipients (approximately five sites per focus area) to serve as implementation sites where one intervention strategy per site will be piloted. The piloted intervention strategies will be evaluated through the companion funding opportunity announcement titled Using Innovative Intervention Strategies to Improve Health Outcomes among People with HIV – Evaluation Center (2iS EC; HRSA-21-068). Ultimately, the 2iS EC’s evaluation findings will determine dissemination plans for the replication tools developed by the 2iS CCTA. Please review this companion announcement for more information about the role of the 2iS EC. You may also review the previous initiative for which this is a competing continuation (HRSA-17-044; HRSA-17-049). 2iS Focus Areas This initiative will focus on three (3) priority populations and one (1) area of opportunity to improve service delivery. Combined, these four (4) focus areas are: 1) Improving HIV health outcomes for people with substance use disorder 2) Improving HIV health outcomes for lesbian, gay, bisexual, transgender, or queer (LGBTQ+) youth 3) Improving HIV health outcomes for people who are or have been incarcerated 4) Improving HIV health outcomes by using telehealth services To identify implementation sites to pilot test the intervention strategies identified across the four (4) focus areas, the 2iS CCTA will be responsible for soliciting, selecting, issuing, and monitoring subawards of up to $190,000/year each for up to twenty (20) RWHAP recipients or subrecipients (hereafter referred to as “subawardees”), or up to five (5) per focus area. The 2iS CCTA will select subawardees based on a demonstrated need and capacity to implement one intervention strategy from one focus area through a competitive application process. The 2iS CCTA will provide TA to the selected subawardees to support successful uptake of the intervention strategy and engagement of clients. The 2iS CCTA will also develop dissemination products that will support the rapid replication of intervention strategies found to be successfully implemented and effective at improving client outcomes in subawardee sites. The companion 2iS EC cooperative agreement (HRSA-21-068) will evaluate the uptake, implementation and associated client outcomes of these intervention strategies at the subawarded sites. Please review the related 2iS EC (HRSA-21-068) announcement to understand the collaborative work between the 2iS CCTA and the 2iS EC.

View more details on this opportunity.

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Department of Health and Human Services – Health Resources and Services Administration – Rural Communities Opioid Response Program – Implementation

Proposal Due Date: March 12, 2021

Expected Number of Awards: 78

Estimated Total Program Funding: $78,000,000

Award Ceiling: $1,000,000

Award Floor:

Funding Opportunity Number: HRSA-21-088

Purpose: The Rural Communities Opioid Response Program (RCORP) is a multi-year initiative by the Health Resources and Services Administration (HRSA) aimed at reducing the morbidity and mortality of substance use disorder (SUD), including opioid use disorder (OUD), in high risk rural communities. This notice announces the opportunity to apply for funding under RCORP-Implementation. This funding opportunity, RCORP Implementation, will advance RCORP’s overall goal by strengthening and expanding SUD/OUD prevention, treatment, and recovery services to enhance rural residents’ ability to access treatment and move towards recovery.

In 2017, the U.S. Department of Health and Human Services (HHS) published a five-point Strategy to Combat Opioid Abuse, Misuse, and Overdose, which outlines concrete steps local communities can take to address the opioid epidemic. In alignment with the HHS Five-Point Strategy, and as part of the RCORP initiative, RCORP-Implementation award recipients will implement a set of core SUD/OUD prevention, treatment, and recovery activities, as outlined in Program-Specific Instructions. These activities incorporate evidence-based, promising, and innovative approaches proven to reduce the morbidity and mortality associated with opioid use disorder including overdose, such as naloxone distribution and other harm reduction services, and Medication-Assisted Treatment (MAT).

Given the complex and multifaceted nature of SUD/OUD, as well as the need to secure community buy-in and generate adequate patient volume to sustain services, HRSA requires that applicants be part of broad, multi-sectoral consortia. For the purposes of RCORP-Implementation, a consortium is an organizational arrangement among four or more separately owned domestic public or private entities, including the applicant organization, with established working relationships. The entities, including the applicant organization, must all have different Employment Identification Numbers (EINs).1

Consortia should be able to operationalize their proposed work plans immediately upon receipt of award.

The target population for the award is: 1) individuals who are at risk for, have been diagnosed with, and/or are in treatment and/or recovery for OUD; 2) their families and/or caregivers; and 3) other community members2 who reside in HRSA-designated rural areas, as defined by the Rural Health Grants Eligibility Analyzer

Applicants are encouraged to include populations that have historically suffered from poorer health outcomes, health disparities, and other inequities, as compared to the rest of the target population, when addressing SUD in the proposed service area. For

1 Tribal entities may be exempt from this requirement. Please reference Eligible Applicants for more information.

2 Applicants are encouraged to include individuals in the community who are involved in improving health care in rural areas.

example, a recent study found that more rural racial/ethnic minorities reported their health as fair or poor, that they were unable to see a physician in the past 12 months because of cost, and that they did not have a personal health care provider compared to their non-Hispanic white counterparts.3 Examples of these populations include, but are not limited to, racial and ethnic minorities, people/persons experiencing homelessness, pregnant women, youth and adolescents, etc.

The primary focus of the RCORP-Implementation award program is OUD. However, recognizing that many individuals with OUD are polysubstance users, or have other co-occurring conditions, consortia may also use RCORP-Implementation support to help address other SUD-related needs of the target population of individuals and families affected by OUD. Applicants should link any additional activities they propose to the needs of their target population and service area. Please note that no competitive advantage, funding priority, or preference is associated with proposing activities beyond the core/required activities outlined in Section IV.2.

HRSA expects that consortia funded by RCORP-Implementation will sustain the strengthened and/or expanded level of SUD/OUD-related services in rural areas made possible by this funding opportunity both during and beyond the period of performance. Over the course of the three-year period of performance, RCORP-Implementation award recipients will complete detailed plans for sustaining their consortia and SUD/OUD services beyond the RCORP-Implementation period of performance.

Finally, RCORP-Implementation award recipients are expected to work closely with a HRSA-funded technical assistance (TA) provider throughout the three-year period of performance. Targeted TA is provided to each award recipient at no additional cost, and is intended to help recipients achieve desired project outcomes, sustain services, align their performance reporting/evaluative activities, implement quality improvement efforts, and overcome challenges to project implementation. HRSA will provide more information about TA support upon receipt of award.

View more details on this opportunity. ________________________________________________________

Department of Health and Human Services – National Institutes of Health – NIDCD Research Dissertation Fellowship for Au.D. Audiologists (F32)

Proposal Due Date: April 8, 2021

Expected Number of Awards:

Estimated Total Program Funding:

Award Ceiling:

Award Floor:

Funding Opportunity Number: PAR-21-093

Purpose: The purpose of the NIDCD Research Dissertation Fellowship for Au.D. Audiologists (F32) program is to support a comprehensive, rigorous biomedical research training, and dissertation research leading to a research doctorate (i.e., Ph.D.) in the biomedical, behavioral, or clinical sciences. This Funding Opportunity Announcement (FOA) does not allow applicants to propose to lead an independent clinical trial, but does allow applicants to propose research experience in a clinical trial led by a sponsor or co-sponsor.

View more details on this opportunity. ________________________________________________________

Department of Health and Human Services – National Institutes of Health – Limited Competition: National Institute on Aging (NIA) Late Onset of Alzheimers Disease (LOAD) Family-Based Study (FBS) (U24 Clinical Trial Not Allowed)

Letter of Intent Due Date: January 17, 2021

Proposal Due Date: February 17, 2021

Expected Number of Awards:                                        1

Estimated Total Program Funding: $3,500,000

Award Ceiling: $2,400,000

Award Floor:

Funding Opportunity Number: RFA-AG-22-001

Purpose: This Funding Opportunity Announcement (FOA) invites applications specific to infrastructure to support the Alzheimer’s Disease Sequencing Project (ADSP) and related to data collection, longitudinal follow-up, ascertainment of antecedent risk factors, and the characterization of additional relatives from families multiply affected by Alzheimer’s disease and related dementias (AD/ADRD) in order to expand the existing NIA Late Onset of AD Family Based Study sample set.

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Department of Health and Human Services – National Institutes of Health – NIDCD Early Career Research (ECR) Award (R21 Clinical Trial Optional)

Proposal Due Date: February 26, 2021

Expected Number of Awards:

Estimated Total Program Funding:

Award Ceiling:

Award Floor:

Funding Opportunity Number: PAR-21-107

Purpose: The NIDCD Early Career Research (ECR) Award (R21) is intended to support both basic and clinical research from scientists who are beginning to establish an independent research career. It cannot be used for thesis or dissertation research. The research must be focused on one or more of the areas within the biomedical and behavioral scientific mission of the NIDCD: hearing, balance, smell, taste, voice, speech, or language. The NIDCD ECR Award R21 grant mechanism supports different types of projects including secondary analysis of existing data; small, self-contained research projects; development of research methodology; translational research; outcomes research; and development of new research technology. Irrespective of the type of project, the intent of the NIDCD ECR Award R21 is for the Program Director(s)/Principal Investigator(s) (PD(s)/PI(s)) to obtain sufficient preliminary data for a subsequent R01 application.

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Department of Health and Human Services – National Institute of Health – NIDA Translational Avant-Garde Award for Development of Medication to Treat Substance Use Disorders (UG3/UH3 Clinical Trial Optional)

Letter of Intent Due Date: 30 days prior to application due date

Proposal Due Date: July 26, 2021

Expected Number of Awards: 2

Estimated Total Program Funding: $2,000,000

Award Ceiling: $1,000,000

Award Floor:

Funding Opportunity Number: PAR-21-092

Purpose: The purpose of this award is to support outstanding basic and/or clinical researchers with the vision and expertise to translate research discoveries into medications for the treatment of Substance Use Disorders (SUDs) stemming from tobacco, cannabis, cocaine, methamphetamine, heroin, or prescription opiate use.  Eligible applicants must demonstrate the ability to develop molecules with the potential to treat SUDs and advance them in the drug development continuum. The ultimate goal of this FOA is to bring molecules closer to FDA approval.

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Department of Health and Human Services – National Institute of Health – Countermeasures Against Chemical Threats (CounterACT) Research Centers of Excellence (U54 Clinical Trial Optional)

Letter of Intent Due Date: 30 days prior to application due date

Proposal Due Date: September 14, 2021

Expected Number of Awards:

Estimated Total Program Funding:

Award Ceiling: $1,750,000

Award Floor:

Funding Opportunity Number: PAR-20-316

Purpose: This Funding Opportunity Announcement (FOA) encourages applications for Countermeasures Against Chemical Threats (CounterACT) Research Centers of Excellence (U54s). The mission of the CounterACT program is to foster and support research and development of new and improved therapeutics for chemical threats. Chemical threats are toxic chemicals that could be used in a terrorist attack or accidentally released from industrial production, storage or shipping. They include traditional chemical warfare agents, toxic industrial chemicals, pharmaceutical-based agents, and pesticides.  The scope of the research includes target and candidate identification and characterization, through candidate optimization and demonstration of in vivo efficacy consistent with the product’s intended use in humans. For applicants submitting U54 renewal applications, research under this FOA should culminate in an optimized lead compound ready for advanced development. The Centers will contain at least three research projects supported by an administrative core, up to three optional scientific cores, and a research education core.  Each research project must include milestones that create discrete go or no-go decision points in a progressive translational study plan.

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Department of Health and Human Services – Substance Abuse and Mental Health Services Administration – National Child Traumatic Stress Initiative – National Center for Child Traumatic Stress – Category I, National Center for Child Traumatic Stress Cooperative Agreement

Proposal Due Date: February 12, 2021

Expected Number of Awards: 1

Estimated Total Program Funding: $6,000,000

Award Ceiling: $6,000,000

Award Floor:

Funding Opportunity Number: SM-21-008

Purpose: The Substance Abuse and Mental Health Services Administration, Center for Mental Health Services is accepting applications for fiscal year (FY) 2021 National Child Traumatic Stress Initiative (NCTSI) – Category I, National Center for Child Traumatic Stress (National Center) cooperative agreement. The purpose of the National Center is to develop and maintain a collaborative network structure, support resource and policy development and dissemination, and coordinate the network’s national child trauma education and training efforts.

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Department of Health and Human Services – Substance Abuse and Mental Health Services Administration – National Child Traumatic Stress Initiative – National Child Traumatic Stress Initiative – Category II, Treatment and Service Adaptation (TSA) Centers

Proposal Due Date: February 12, 2021

Expected Number of Awards: 29

Estimated Total Program Funding: $17,853,000

Award Ceiling: $17,853,000

Award Floor:

Funding Opportunity Number: SM-21-009

Purpose: The Substance Abuse and Mental Health Services Administration (SAMHSA), Center for Mental Health Services (CMHS), is accepting applications for fiscal year (FY) 2021 National Child Traumatic Stress Initiative (NCTSI) – Category II, Treatment and Service Adaptation (TSA) Centers (Short Title: NCTSI-II). The purpose of the TSA Centers is to provide national expertise for specific types of traumatic events, population groups, and service systems, and support the specialized adaptation of effective evidence-based treatment and service approaches for communities across the nation.

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Department of Health and Human Services – Substance Abuse and Mental Health Services Administration – National Child Traumatic Stress Initiative – Category III, Community Treatment and Service (CTS) Centers

Proposal Due Date: February 12, 2021

Expected Number of Awards: 62

Estimated Total Program Funding: $24,903,000

Award Ceiling: $24,903,000

Award Floor:

Funding Opportunity Number: SM-21-010

Purpose: The Substance Abuse and Mental Health Services Administration (SAMHSA), Center for Mental Health Services (CMHS), is accepting applications for fiscal year (FY) 2021 National Child Traumatic Stress Initiative (NCTSI) – Category III, Community Treatment and Service (CTS) Centers (Short Title: NCTSI – III). The purpose of this program is to provide and increase access to effective trauma-focused treatment and services systems in communities for children and adolescents, and their families who experience traumatic events throughout the nation.

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Department of Health and Human Services – Substance Abuse and Mental Health Services Administration – Project AWARE (Advancing Wellness and Resiliency in Education) State Education Agency Grants

Proposal Due Date: February 15, 2021

Expected Number of Awards: 5

Estimated Total Program Funding: $9,943,394

Award Ceiling: $1,800,000

Award Floor:

Funding Opportunity Number: SM-21-006

Purpose: The Substance Abuse and Mental Health Services Administration (SAMHSA) Center for Mental Health Services (CMHS) is accepting applications for fiscal year (FY) 2021 Project AWARE (Advancing Wellness and Resilience in Education) – State Education Agency (SEA) grants (Short Title: AWARE-SEA). The purpose of this program is to build or expand the capacity of State Educational Agencies, in partnership with State Mental Health Agencies (SMHAs) overseeing school-aged youth, and with three local education agencies (LEAs) to (1) increase awareness of mental health issues among school-aged youth; (2) provide training for school personnel and other adults who interact with school-aged youth to detect and respond to mental health issues; and (3) connect school-aged youth who may have behavioral health issues (including serious emotional disturbance [SED] or serious mental illness [SMI]), and their families, to needed services. SAMHSA expects that this program will focus on partnerships and collaboration between state and local systems to promote the healthy development of school-aged youth and prevent youth violence.

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Department of Health and Human Services – Substance Abuse and Mental Health Services Administration – Resiliency In Communities After Stress and Trauma

Proposal Due Date: February 15, 2021

Expected Number of Awards: 6

Estimated Total Program Funding: $6,925,509

Award Ceiling: $1,000,000

Award Floor:

Funding Opportunity Number: SM-21-012

Purpose: The Substance Abuse and Mental Health Services Administration (SAMHSA), Center for Center for Mental Health Services (CMHS), is accepting applications for fiscal year (FY) 2021 Resiliency in Communities After Stress and Trauma (Short Title: ReCAST Program) grants. The purpose of this program is to assist high-risk youth and families and promote resilience and equity in communities that have recently faced civil unrest through implementation of evidence-based, violence prevention, and community youth engagement programs, as well as linkages to trauma-informed behavioral health services. The goal of the ReCAST Program is for local community entities to work together in ways that lead to improved behavioral health, empowered community residents, reductions in trauma, and sustained community change.

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Department of Health and Human Services – Substance Abuse and Mental Health Services Administration – Building Communities of Recovery

Proposal Due Date: February 15, 2021

Expected Number of Awards: 19

Estimated Total Program Funding: $3,913,423

Award Ceiling: $200,000

Award Floor:

Funding Opportunity Number: TI-21-004

Purpose: The Substance Abuse and Mental Health Services Administration (SAMHSA), Center for Substance Abuse Treatment (CSAT), is accepting applications for fiscal year (FY) 2021 Building Communities of Recovery (Short Title: BCOR). The purpose of this program is to mobilize resources within, and outside of, the recovery community to increase the prevalence and quality of long-term recovery support from substance abuse and addiction. These grants are intended to support the development, enhancement, expansion, and delivery of, recovery support services (RSS) as well as promotion of, and education about recovery. Programs will be principally governed by people in recovery from substance abuse and addiction who reflect the community being served.

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Department of Health and Human Services – Substance Abuse and Mental Health Services Administration – Rural Emergency Medical Services Training Grant

Proposal Due Date: February 16, 2021

Expected Number of Awards: 25

Estimated Total Program Funding: $5,000,000

Award Ceiling: $200,000

Award Floor:

Funding Opportunity Number: TI-21-005

Purpose: The Substance Abuse and Mental Health Services Administration (SAMHSA), Center for Substance Abuse Treatment, is accepting applications for fiscal year (FY) 2021 Rural Emergency Medical Services Training grants (Short Title: EMS Training). The purpose of this program is to recruit and train emergency medical services (EMS) personnel in rural areas. SAMHSA recognizes the great need for emergency services in rural areas and the critical role EMS personnel serve across the country.

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