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Member Research and Reports

Member Research and Reports

Discordance between LDL and HDL Cholesterol Evaluated by UAB

Although low-density lipoprotein cholesterol (LDL-C) is recommended as the primary marker to guide lipid-lowering therapy, some data suggest non-high-density lipoprotein cholesterol (non-HDL-C) may better reflect coronary heart disease risk. Discordance between these measures has not been evaluated. Dr. Meredith Kilgore, chair and professor in the department of health care organization and policy at the University of Alabama at Birmingham – teamed with Dr. Paul Muntner, professor, and Mr. Pradeep Sharma, statistician I in the department of epidemiology; and Dr. Vera A. Bittner, professor in the department of medicine – used data from the National Health and Nutrition Examination Surveys 2005-2010 to examine the discordance between these lipid parameters. Elevated levels of non-HDL-C and LDL-C were defined by using the 2004 Adult Treatment Panel III guidelines.