Dr. Brian Lee, associate professor of the Department of Epidemiology and Biostatistics in the Drexel University Dornsife School of Public Health and a fellow of the A.J. Drexel Autism Institute, along with an international team of investigators, was awarded a $1.7 million R01 grant by the National Institute of Neurological Disorders and Stroke to conduct a pharmacoepidemiology study of maternal antiepileptic medication use during pregnancy and risk of autism spectrum disorders (ASD).
The management of epilepsy during pregnancy is challenging, given the need to balance risks and benefits of treatment for both mother and child. Dr. Lee and his collaborators at the University of Bristol and the Karolinska Institute will study data on medication use and health outcomes including ASD for nearly 3 million mother-child pairs in the United Kingdom and Sweden. The study aims to estimate the health risks for mother and child associated with taking or not taking antiepileptic treatment regimens during pregnancy. The research should contribute to the evidence base for clinical recommendations regarding the care for women with epilepsy during pregnancy.Tags: Friday Letter Submission, Publish on June 21