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Member Research & Reports

Member Research & Reports

Emory: Study Finds Various Antihypertension Medication Classes to Be Similarly Effective with Nuanced Differences

A recent study published in JAMA Network Open found that the effects of various antihypertension medicines were similar with nuanced differences. The authors conducted a systematic review and network meta-analysis of 46 randomized clinical trials spanning 248,887 patients with hypertension and no substantial comorbidities comparing the effectiveness of antihypertension medication classes. Findings showed angiotensin-converting enzyme inhibitors, dihydropyridine calcium channel blockers, and diuretics were all similarly effective at reducing cardiovascular death, stroke, and overall cardiovascular events. Angiotensin-converting enzyme inhibitors and diuretics were the most effective at reducing myocardial infarction and revascularization.

Emory University Rollins School of Public Health authors on the article included Drs. Karla I. Galaviz, Matthew J. Magee, K.M. Venkat Narayan, and Mohammed K. Ali.

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