Extensive scientific evidence on the health impacts from exposure to ozone has been used to support the regulation of ozone under the Clean Air Act for nearly half a decade. While the major research focus has been on ozone’s detrimental effects on the lungs, a large 2016 study has suggested ozone exposure may have impacts on the cardiovascular system as well.

EPA-funded research has found a potential relationship between long-term exposures to ground level ozone and the changes over time in the health of arteries that feed both the brain (carotid arteries in the neck) and heart (coronary arteries).

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