Venous thromboembolism (VTE) is increasingly being diagnosed in pediatric and young adult patients. Like in older adults, VTE in young patients arises from clinical conditions that lead to venous stasis, endothelial damage, or hypercoagulable states—i.e., the triad of Virchow. However, there are distinct differences in VTE among the pediatric and young adult population compared to older adults, including the prevalence of acquired thrombophilia and diagnosed genetic thrombophilias, as well as the prevalence of venous anatomic conditions related to the VTE occurrence. The risks for some adverse outcomes from VTE also differ between young and older patients, indicating the need for development of an evidence base for VTE treatment and prevention strategies for pediatric and young adult patients.
In this webinar, Dr. Goldenberg will present an overview of VTE in children and young adults. He will discuss what is currently known about risk factors, diagnosis, treatment, outcomes, prognostic factors, and prevention strategies. He will also discuss what’s known about obesity and its relationship to VTE risk in young patients. Finally, he will address approaches to the early diagnosis and optimal management of challenging scenarios in young-onset VTE, including May-Thurner anomaly and venous thoracic outlet syndrome.
1.Describe differences among children, young adults, and older adults with respect to incidence, risk factors, presentations, the evidence base for treatment recommendations, and outcomes of VTE.
2. State recent findings and gaps in knowledge of the relationship between overweight/obesity and both VTE risk and VTE outcomes in children.
3. List the presentations and treatment approaches for challenging VTE scenarios occurring in children and young adults in which there is an underlying venous anatomic condition—specifically, May-Thurner anomaly and venous thoracic outlet syndrome