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Member Research and Reports

Member Research and Reports

George Mason: Having Children Can Make Women’s Telomeres Seem 11 Years Older

Researchers at George Mason University recently published a study in Human Reproduction that reported finding shorter telomeres compared to women who had not given birth. Telomeres are the end caps of DNA on our chromosomes, which help in DNA replication and get shorter over time. The length of telomeres has been associated with morbidity and mortality previously, but this is the first study to examine links with having children.

[Photo: Dr. Anna Z. Pollack]

The authors reported that telomeres among women who had children were the equivalent of 11 years shorter. This was a larger change than has been reported by other research groups for smoking or obesity. Dr. Pollack pointed out that, “with cross-sectional data, we can’t tell if having children is related to shortening of telomeres or merely whether women who have children start out with shorter telomeres.” Additional factors to consider include stress and social support, as well as whether similar findings are seen in men.

The paper utilized data from the National Health and Nutrition Examination Survey, which is a nationally representative study in the United States. Dr. Anna Z. Pollack, lead author of the study, notes that these findings, “are preliminary and should be confirmed with prospective studies.” The study was co-authored by George Mason alumna, Ms. Kelsey Rivers, who completed the research study through a George Mason University Undergraduate Research Scholars Program award.

The article, “Parity associated with telomere length among US reproductive age women“, is available online.