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Member Research and Reports

Harvard: China Facing Epidemic of Heart Disease, Stroke

A 20-year rise in cardiovascular disease (CVD) in China appears to have been spurred largely by increases in high blood pressure, according to a new study from Harvard T.H. Chan School of Public Health. Increasing body mass index (BMI), decreasing physical activity, a high prevalence of smoking, and unhealthy diet have also contributed to the growing burden of CVD — now the leading cause of death in China.

This is the first large study to analyze a wide range of dietary, lifestyle, and metabolic risk factors that may be impacting CVD burden in China. The authors suggested that major changes in Chinese society — including a dramatic shift from a traditional to a more “Western” diet and lifestyle and rapid urbanization and industrialization — may have contributed to the jump in cardiovascular diseases, such as heart attack and stroke. These changes have been accompanied by marked increases in high cholesterol, obesity, and type 2 diabetes among the Chinese population.

The study was published August 15 in the Journal of the American College of Cardiology.

“We described trends from 1991 to 2011 in dietary and other lifestyle risk factors for CVD in China and projected how these trends might play out from 2011 to 2031,” said Dr. Yanping Li, research scientist in the department of nutrition at Harvard Chan School and lead author of the study. “Our estimates suggest that the continued rise in high blood pressure, an increasingly sedentary lifestyle, increasing obesity, and worsening dietary trends will add millions of new cases of heart attacks and stroke over the next two decades.”

The researchers analyzed data collected over a 20-year period, from 1991-2011, from 26,000 people living in nine Chinese provinces, as part of the China Health and Nutrition Survey. They looked at 17 dietary and lifestyle risk factors that have been previously linked with heart attack and stroke — including high systolic blood pressure, high cholesterol, high blood glucose, high BMI, low physical activity, smoking, and 11 dietary factors — and analyzed that data along with information on CVD-related disease and death incidence extracted from the China Health Statistical Yearbook and the National Population Census.

The study found that high blood pressure, high cholesterol, and high blood glucose accounted for most of the CVD disease burden in China in 2011. That year, those three risk factors were associated, respectively, with 3.1, 1.4, and 0.9 million new cases of heart attack or stroke. Of 6.8 million Chinese over age 35 who died in 2011, about three million of the deaths — 44 percent — were CVD-related.

The researchers estimated that high blood pressure alone was responsible for roughly 40 percent of heart attacks or stroke. High blood pressure has jumped dramatically in China over the past three decades, the authors noted: In 1979, its prevalence in the population was 7.7 percent; by 2010 it was 33.5 percent — comparable to that among U.S. adults.

“China is facing a rising epidemic of cardiovascular disease and it shows no sign of abating,” said senior author Dr. Frank Hu, professor of nutrition and epidemiology at Harvard Chan School. “It’s imperative to continue to monitor the problem, which has serious social and economic consequences. Prevention of chronic diseases through promoting healthy diet and lifestyle should be elevated to a national public policy priority.”

Funding for the study came from the Swiss Re Foundation.

Read more: https://www.hsph.harvard.edu/news/press-releases/china-heart-disease-stroke-epidemic-hu-li/