Dr. Martin Lindquist, professor in the Johns Hopkins Bloomberg School of Public Health’s department of biostatistics, has been awarded $8.1 million by the National Institutes of Health (NIH) to investigate the biological characteristics underlying the transition from acute to chronic pain. The grant is part of NIH’s four-year $40.4 million Acute to Chronic Pain Signatures (A2CPS) program.
Chronic pain is a significant public health problem and the prevention of chronic pain after an acute pain event is a major challenge in pain management. The number of people who transition from acute to chronic pain after an acute pain event has contributed to the current opioid epidemic. The ability to predict which patients are more susceptible or resilient to the development of chronic pain will provide insights that could transform acute pain management care as well as help prevent chronic pain.
The A2CPS consortium will consist of five centers, four data acquisition centers, and a data integration and analysis center that which will be based in the Bloomberg School’s department of biostatistics with Dr. Lindquist serving as principal investigator. The A2CPS consortium will perform a longitudinal prospective study on 3,600 subjects who experience acute pain from either a specific surgical procedure or a specific musculoskeletal trauma.
Dr. Lindquist is actively involved in developing new analysis methods to enhance our ability to understand brain function using human neuroimaging. A large focus of his work has been on how the brain processes pain.Tags: Friday Letter Submission, Publish on September 27