New research from the University of Kentucky College of Public Health demonstrates that significant and substantial spatial variation exists in the histological types of lung cancer diagnosed in Kentucky, a state with an especially high burden of lung cancer. Using data from the Kentucky Cancer Registry, Dr. W. Jay Christian and colleagues reviewed types of lung cancer diagnosed across Kentucky from 1995 to 2014.
Along with significantly higher risk for most types of lung cancer in high poverty areas, likely related to higher smoking rates, investigators observed recent increases in risk for adenocarcinoma in the North-Central region – an area that has lower smoking and obesity rates than the rest of the state, and is additionally more urban and affluent. Suspecting an environmental cause for this increased adenocarcinoma rate, the authors conclude that research should examine data from additional cancer registries in other states and explore potential risks associated with air pollution and other environmental exposures in metropolitan areas to better understand spatial and temporal trends in lung cancer histology.
Dr. W. Jay Christian, assistant professor of epidemiology, is first and corresponding author of “Spatiotemporal Analysis of Lung Cancer Histological Types in Kentucky, 1995–2014 ”, published in Cancer Control . Co-authors are Dr. Nathan Vanderford, UK College of Pharmacy; Dr. Jaclyn McDowell, epidemiology adjunct faculty and Kentucky Cancer Registry; Dr. Bin Huang, Cancer Biostatistics; Dr. Eric Durbin, Kentucky Cancer Registry; Dr. Kimerly Absher, UK College of Medicine; Courtney J. Walker, epidemiology graduate student; and Dr. Susanne Arnold, UK College of Medicine.Tags: Friday Letter Submission, Publish on December 27