A new study from the University of Kentucky College of Public Health investigates the spatial and temporal distribution of lung cancer histological types in Kentucky, a largely rural state with high rates of smoking and obesity, to discern population-level trends that might reflect variation in these and other risk factors. Results of the investigation appear in a new paper by Dr. W. Jay Christian, et al, published in Cancer Control.
Using data from the Kentucky Cancer from 1995 through 2014, investigators adjusted for age, gender, and race, to characterize risk for specific histological types — small cell, adenocarcinoma, squamous cell, and other types — throughout Kentucky, and compared to maps of risk factors.
The results of the study demonstrates that significant and substantial spatial variation exists in the histological types of lung cancer diagnosed in Kentucky, a state with an especially high burden of lung cancer. Along with significantly higher risk for most types of lung cancer in high poverty areas, likely related to higher smoking rates, we observed recent increases in risk for adenocarcinoma in a region that has lower smoking and obesity rates than the rest of the state and is additionally more urban and affluent.Friday Letter Submission