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Faculty & Staff Honors

Faculty & Staff Honors

Michigan Researchers Receive $2.5 million Grant from the National Institute on Minority Health and Health Disparities

Researchers from UM SPH as well as from the Medical School and other UM research groups have developed a project that will test the efficacy of implementing a Stroke Ready program on early treatment and stoke outcomes in Flint, MI.


[Photo: Community advisory board members, including Dr. Skolarus (back row, second from left), who have partnered on projects to boost stroke treatment and awareness in Flint]

Following the onset of a stroke, restoring blood flow to the brain as quickly as possible is critical for preventing disability and improving the chances of recovery. This crucial window for treatment is a narrow one – about 4 ½ hours – and the earlier the treatment, the better the outcome.

More than 7 million stroke survivors in the U.S. are left with persistent disability after a stroke, such as weakness or speech and language problems, often because treatment was given too late, or not at all. “Time lost is brain lost,” as one saying goes. Each minute of delay results in an estimated loss of 1.9 million neurons, which, over the course of an hour without treatment, can be roughly compared to 3.6 years of normal brain aging.

Stroke treatments must be administered in the emergency department, often in the form of a “clot-busting” drug called tPA, and can reduce the risk of disability by more than 30 percent. Yet because of a variety of barriers to timely evaluation and treatment, fewer than 5 percent of those who experience a stroke ever receive these therapies.

Under a five-year, $2.5 million grant from the National Institute on Minority Health and Health Disparities, this team of University of Michigan researchers along with community partners is embarking on a novel project to increase acute stroke treatment rates in the community of Flint, Michigan.

Led by Dr. Lesli Skolarus, an associate professor of neurology and a board-certified vascular neurologist, the team is testing a hospital- and community-based intervention called the “Stroke Ready” program that will attempt to address delays that can occur before and after arrival to the hospital, ultimately reducing the likelihood of stroke treatment and lessening its effectiveness.

Because one of the most significant opportunities to increase stroke treatment rates lies in those critical first few moments immediately following a suspected stroke, a primary goal of the program aims to boost community “stroke preparedness” by helping people recognize the symptoms of stroke and encouraging them to call 9-1-1 immediately to get help on its way.

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