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Member Research and Reports

Member Research and Reports

Minnesota Assistant Professor Analyzes Velocity for Processive Motor Proteins

Dr. John Hughes, assistant professor of biostatistics at the University of Minnesota School of Public Health, is the lead author of a new analysis that seeks to better understand the behavior of processive motor proteins. Processive motor proteins are ATP-powered biological nanomachines that drive many forms of movement in living organisms. By taking “steps” along a microtubule, the motor proteins provide rapid transport of cargoes through the crowded cytoplasm of a cell. Chemical reactions together with a process called tethered diffusion govern the duration and direction of the (random number of) steps taken before the motor dissociates from the microtubule.