A new Northwestern Medicine study exploring the benefits of targeted muscle reinnervation (TMR) – a series of nerve transfers that permits intuitive control of upper-limb prostheses – could change the way surgical amputations are performed in the future. The $2.5 million project led by Dr. Gregory Dumanian, chief of plastic surgery, builds upon his recently published work in Clinical Orthopaedics and Related Research. In that investigation, Dr. Dumanian revealed that 14 of 15 patients suffering from neuroma pain experienced complete resolution of discomfort after TMR. The remaining patient’s pain was improved but not resolved. In several subjects, phantom discomfort from limb loss also improved.