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Member Research and Reports

Member Research and Reports

NYU: Smokeless Tobacco Users Exposed to Higher Concentrations of Tobacco Toxicants

A study co-authored by Dr. Raymond Niaura, interim chair of the Department of Epidemiology and professor of social and behavioral sciences at the New York University School of Global Public Health, was published in Cancer Epidemiology, Biomarkers, & Prevention titled “Biomarkers of Exposure among Adult Smokeless Tobacco Users in the Population Assessment of Tobacco and Health Study (Wave 1, 2013-14).”

Monitoring population-level toxicant exposures from smokeless tobacco (SLT) use is important for assessing population health risks due to product use. This study assesses tobacco biomarkers of exposure (BOEs) among SLT users from the Wave 1 (2013-14) of the Population Assessment of Tobacco and Health (PATH) Study. 

Findings indicate that SLT users have significantly higher concentrations of biomarkers of exposure to nicotine, tobacco-specific nitrosamines (TSNAs) and polycyclic aromatic hydrocarbons (PAHs) compared to never tobacco users; significant dose-response relationships between frequency of SLT use and biomarker concentrations were also reported among exclusive SLT daily users. Exclusive SLT daily users have higher geometric mean concentrations of total nicotine equivalent-2 (TNE2) and TSNAs than exclusive cigarette daily smokers. In contrast, geometric mean concentrations of PAHs and volatile organic compounds (VOCs) s were substantially lower among exclusive SLT daily users than exclusive cigarette daily smokers.

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