In a recent article in Public Health Reports, University of Kentucky College of Public Health and Emory University Rollins School of Public Health researchers explore the feasibility of web- and community-based strategies to recruit rural, young adult people who use drugs (PWUD) into epidemiologic research. PWUD from rural Kentucky were recruited using web-based peer referral and community-based strategies such as cookouts, flyers, and street outreach. Recruitment yielded 410 completed screening entries. Cookouts and subsequent web-based peer referrals accounted for the highest proportion of these entries. Study findings highlighted the need to complement web-based recruitment methods with context-tailored, street-outreach activities to recruit rural PWUD.