In a recent article in Public Health Reports, Dr. Garrett Beeler Asay and Ms. Erin Abramsohn from the Office of the Associate Director for Policy, Centers for Disease Control and Prevention (CDC), Drs. David Homa and Xin Xu from the Office on Smoking and Health, CDC, and Dr. Guijing Wang from Division for Heart Disease and Stroke Prevention, CDC provided an estimate for the reduction in the number of hospitalizations for acute myocardial infarction and stroke and the associated health care costs resulting from reducing the number of smokers in the U.S. federal workforce during a five-year period. They developed a five-year spreadsheet-based cohort model with parameter values taken from past literature and the analysis of the national survey data. Authors found that a five percentage-point reduction in smoking prevalence could result, over a five-year period, in a significant reduction in the number of hospitalizations for and deaths from acute myocardial infarction and stroke, as well as in significant costs averted including those associated with medical expenses, absenteeism, and productivity. Authors conclude that federal government should further leverage tobacco-free policies and promote current federal employee tobacco cessation benefits to encourage employees to quit smoking.