In a recent article in Public Health Reports, Drs. Sharon Horesh Bergquist and Felipe Lobelo of Emory University discuss the balance between DNA-centered and environmental/behavioral approaches to personalized medicine, which aims to individualize healthcare based on one’s proneness to disease and response to treatment. Authors note that chronic diseases are complex traits dependent not only on genetic risk, but also on behavioral, environmental, and social determinants and that reductionist efforts to isolate causative and predictive genetic associations have not been very successful. They conclude that genomic interventions that take into account environmental interactions will be needed to unlock the full potential of genomic medicine for chronic disease prevention.
Read the full article here.
Public Health Reports (PHR) is the official journal of the Office of the U.S. Surgeon General and the U.S. Public Health Service and has been published since 1878. It is published bimonthly, plus supplement issues, through an official agreement with the Association of Schools and Programs of Public Health. PHR’s mission is to facilitate the movement of science into public health practice and policy to positively affect the health and wellness of the American public.
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