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Member Research & Reports

Member Research & Reports

Socioeconomic Deprivation and MetS with Inflammation Studied by UAB

Dr. José Fernández, professor and vice chair for education in the department of nutrition sciences at the University of Alabama at Birmingham — collaborating with Dr. Akilah Dulin Keita, assistant professor of behavioral and social sciences at Brown University and former postdoctoral trainee in UAB’s Nutrition Obesity Research Center (NORC) — recently conducted a study examining the association of neighborhood socioeconomic deprivation and metabolic syndrome (MetS) with inflammation. Other UAB co-investigators include Dr. Suzanne E. Judd, associate professor in the department of biostatistics; along with Dr. Virginia J. Howard, professor, and Dr. April P. Carson, assistant professor, in the department of epidemiology. The analysis included 19,079 Black and White participants over the age of 45 at baseline from the national REasons for Geographic And Racial Differences in Stroke Study (REGARDS), which is focused on “learning more about the factors that increase a person’s risk of having a stroke.” Logistic regression examined whether neighborhood deprivation was associated with increased odds of MetS and C-reactive protein (CRP)-MetS.

FernandezJ_UAB ASPPH
[Photo: Dr. José Fernández]

Among Black adults, residing in the most deprived neighborhoods was associated with increased odds of obesity, lower HDL, high blood pressure, elevated fasting glucose, inflammation, and CRP-MetS. Among White adults, neighborhood deprivation was associated with higher waist circumference, lower HDL, higher triglycerides, higher glucose, higher BMI, higher blood pressure, MetS, inflammation, and CRP-MetS.

These findings highlight the role of neighborhood socioeconomic deprivation on MetS and CRP-MetS for black and white adults. The researchers concluded that interventions tailored to address the contextual effects of deprived neighborhoods may reduce the observed neighborhood disparities.

“Associations of Neighborhood Area Level Deprivation with the Metabolic Syndrome and Inflammation among Middle- and Older-Age Adults” was published in December 2014 in the journal BMC Public Health.

Journal article: