Health Promotion, Education and Behavior (HPEB) Professor and SmartState Endowed Chair for Clinical Translational Research Dr. Xiaoming Li (University of South Carolina) will serve as the director for the Analytic Core of a nationwide research program, which has been funded with a $15.7 million grant from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). The five-year award will establish “Scale it Up: Effectiveness-Implementation Research to Enhance HIV-Related Self-Management Among Youth” (1U19HD089875-01)—a research program aimed at the development and assessment of effectiveness of theoretically and developmentally sound interventions focused on improving self-management among HIV-positive and at-risk youth between the ages of 13 through 24. The funding is part of a national research network, Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN), which is devoted to the health and well-being of adolescents and young adults who have HIV or are at risk for HIV infection.
[Photo: Dr. Xiaoming Li]
Dr. Li’s Analytic Core, along with a Management Core and an Implementation Science Core, will provide support to three R01 research projects within the Scale it Up initiative: 1) training providers at HIV clinics to utilize motivational interviewing to promote self-management among HIV-positive and at risk youth (led by Dr. Sylvie Naar at Wayne State University); 2) implementing the Young Men’s Health Project intervention to reduce sexual risk and substance abuse among HIV-negative and bisexual men (led by Dr. Jeffrey Parsons at City University of New York (CUNY) Hunter College); 3) implementing a text message and cellphone support intervention to promote medication adherence among HIV-positive youth (led by Dr. Marvin Belzer of Children’s Hospital of Los Angeles and Dr. Karen MacDonell of Wayne State University).
The multiple principal investigators of Scale it Up include Drs. Naar, Parsons and Bonita Stanton (Seton Hall University). The research will be conducted at multiple adolescent HIV clinical sites in Baltimore, Chicago, Detroit, Los Angeles, Memphis, Miami, New Orleans, Philadelphia, San Diego, Tampa, and Washington D.C. “These research teams will develop, test and bring to practice self-management interventions that positively impact youth HIV prevention and care cascades,” says Dr. Li.
The Analytic Core, which is comprised of a team of experts from seven universities across the country (i.e., University of South Carolina, University of Oregon, Wayne State University, University of Michigan, University of California San Diego, Medical University of South Carolina, CUNY Hunter College), will provide analytic support both within and across the three research projects. The expertise of the Analytic Core includes measurement, qualitative research methods, cost-effectiveness analysis, and intervention trial design and evaluation.