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Member Research and Reports

Member Research and Reports

UIC: Research Highlights Lack of Connection Between Naltrexone and Opioid Receptor Genes

New research co-authored by Dr. Maria Argos, associate professor of epidemiology, found no association between naltrexone, a tobacco cessation drug, and effects on opioid receptor genes.  The study was published in the journal Alcohol and Alcoholism.

The study explored how variations in opioid receptor genes may influence the efficacy of naltrexone in the context of a smoking cessation trial, seeking an association between receptor genes and naltrexone’s effects on smoking quit rate, weight gain and heavy drinking behavior.  The test, involving 280 adults, found no suggestion that genetic variation in opioid-receptors is related to treatment responses to naltrexone in a smoking cessation trial.

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