Researchers from the University of North Carolina at Chapel Hill, Duke University and North Carolina State University have been awarded a five-year, $10.4 million grant by the National Cancer Institute to continue determining ways to design more powerful clinical trials for cancer patients, effectively delivering better and more personalized new therapies to cancer patients sooner.
[Photo: UNC’s Dr. Michael Kosorok (not pictured) leads a collaborative study funded by the National Cancer Institute to determine ways to design more powerful clinical trials for cancer patients, effectively delivering better and more personalized new therapies to cancer patients sooner. Photo courtesy of College of DuPage (Illinois) newsroom]
The award, “Statistical Methods for Cancer Clinical Trials,” was funded originally for $12.5 million in 2010 and is one of NCI’s largest grants of this type.
Dr. Michael R. Kosorok, W.R. Kenan Jr. Distinguished Professor and chair of biostatistics at UNC’s Gillings School of Global Public Health, is the contact principal investigator for the project. Dr. Marie Davidian, William Neal Reynolds Professor of Statistics and director of the Center for Quantitative Sciences in Biomedicine at N.C. State, and Dr. Kouros Owzar, professor of biostatistics and bioinformatics at Duke, are also principal investigators.
The project supports a major collaborative, multidisciplinary effort that takes advantage of the unrivaled concentration of leading statistical and clinical experts across the three institutions and the two highly-rated cancer centers at UNC and Duke.
Other Gillings School biostatistics faculty members in leadership roles on the grant are Dr. Joseph G. Ibrahim, Alumni Distinguished Professor and director of the Center for Innovative Clinical Trials at UNC; Dr. Jianwen Cai, professor and associate chair; and Dr. Danyu Lin, Dennis Gillings Distinguished Professor.
Other schools, departments and centers across the UNC campus are involved on the project, including the UNC Eshelman School of Pharmacy, the Lineberger Comprehensive Cancer Center, the Gillings School’s health policy and management department and others. Leaders also include Dr. Xiaofei Wang, associate professor of biostatistics and bioinformatics at Duke, and Dr. Anastasios A. Tsiatis, Drexel Professor of Statistics at N.C. State.