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Member Research and Reports

Member Research and Reports

UNC Research Demonstrates ‘Guided Missile’ Strategy to Kill Hidden HIV

Researchers at the University of North Carolina at Chapel Hill have deployed a potential new weapon against HIV – a combination therapy that targets HIV-infected cells that standard therapies cannot kill.Using mouse models that have immune systems composed of human cells, researchers led by Dr. J. Victor Garcia, professor of medicine in the UNC School of Medicine and senior author of the study, found that an antibody combined with a bacterial toxin can penetrate HIV-infected cells and kill them even though standard antiretroviral therapy (ART) had no effect. Killing these persistent, HIV-infected cells is a major impediment to curing patients of HIV.