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Member Research and Reports

Member Research and Reports

WashU Review: Lower-Dose Vitamin A Better For Acute Malnutrition

Children with severe acute malnutrition should be given a low-dose regimen of vitamin A supplementation (VAS), new findings from the Brown School at Washington University in St. Louis suggest. Current World Health Organization guidelines recommend high-dose VAS be given on the first day of admission, followed by high-dose VAS on days two and 14 if clinical signs of vitamin A are present. But the Brown School’s review of the literature from 1950-2012 found high-dose VAS could result in adverse effects, such as respiratory infection or diarrhea.